Our goal is to develop scalable analytical methods to capture hidden dynamics of network connectivity and to arrive at biologically meaningful interpretations of massive datasets. This work is done in collaboration with Prof. Schwing's group.
Since complex behavior is a result of coordinated firing in large neuronal networks, we expect the recorded activity to exhibit a rich hidden structure. In a search for complex high dimensional representations, we develop structured machine learning approaches capable of learning the dynamics of the recorded neural network as a whole. Subsequent dimensionality reduction and correlation with behavioral and sensory datasets allows us to extract functional neural circuits and systems involved in complex behavior. Instead of analyzing the neural data based on a pre-conceived biological model, our approach enables efficient reduction to low-dimensional dynamic dataset in a model-unbiased manner.
Discovery of latent dynamic connectivity in brain cortical networks from massive spiking data, bioRxiv, 2023.08. 08.552512, 2023
Unsupervised Discovery of Dynamic Neural Circuits, NeurIPS 2019 Workshop Neuro AI, Openreview
Discovery of dynamic functional connectivity of cortical networks, 2019, Society for Neuroscience